Sufficient minimal model for DNA denaturation: Integration of harmonic scalar elasticity and bond energies
Sufficient minimal model for DNA denaturation: Integration of harmonic scalar elasticity and bond energies
We study DNA denaturation by integrating elasticity — as described by the Gaussian network model — with bond binding energies, distinguishing between different base pairs and stacking energies. We use exact calculation, within the model, of the Helmholtz free-energy of any partial denaturation state, which implies that the entropy of …