MODELING AND OPTIMIZATION OF GENETIC SCREENS VIA RNA INTERFERENCE AND FACS
MODELING AND OPTIMIZATION OF GENETIC SCREENS VIA RNA INTERFERENCE AND FACS
We study mathematically a method for discovering which gene is related to a cell characteristic (“phenotype”) of interest. The method is based on RNA interference – a molecular process for gene deactivation – and on coupling the phenotype with cell fluorescence. A small number of candidate genes are thus isolated, …