A multiscale model of complex endothelial cell dynamics in early angiogenesis
A multiscale model of complex endothelial cell dynamics in early angiogenesis
Abstract We introduce a hybrid two-dimensional multiscale model of angiogenesis, the process by which endothelial cells (ECs) migrate from a pre-existing vascular bed in response to local environmental cues and cell-cell interactions, to create a new vascular network. Recent experimental studies have highlighted a central role of cell rearrangements in …