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Quantitative aerobiologic analysis of an influenza human challenge‐transmission trial

Quantitative aerobiologic analysis of an influenza human challenge‐transmission trial

Despite evidence that airborne transmission contributes to influenza epidemics, limited knowledge of the infectiousness of human influenza cases hinders pandemic preparedness. We used airborne viral source strength and indoor CO2 monitoring from the largest human influenza challenge-transmission trial (EMIT: Evaluating Modes of Influenza Transmission, ClinicalTrials.gov number NCT01710111) to compute an …