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Learning from electronic health records across multiple sites: A communication-efficient and privacy-preserving distributed algorithm

Learning from electronic health records across multiple sites: A communication-efficient and privacy-preserving distributed algorithm

Abstract Objectives We propose a one-shot, privacy-preserving distributed algorithm to perform logistic regression (ODAL) across multiple clinical sites. Materials and Methods ODAL effectively utilizes the information from the local site (where the patient-level data are accessible) and incorporates the first-order (ODAL1) and second-order (ODAL2) gradients of the likelihood function from …