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Variation in the life history strategy of cells underlies tumor’s functional diversity

Variation in the life history strategy of cells underlies tumor’s functional diversity

Abstract Classical r - vs. K -selection theory describes the trade-offs between high reproductive output and competitiveness and guides research in evolutionary ecology 1–5 . While its impact has waned in the recent past, cancer evolution may rekindle it 6–10 . Indeed, solid tumors are an ideal theater for r …