Tailored Graphical Lasso for Data Integration in Gene Network Reconstruction
Tailored Graphical Lasso for Data Integration in Gene Network Reconstruction
Abstract Background Identifying gene interactions is a topic of great importance in genomics, and approaches based on network models provide a powerful tool for studying these. Assuming a Gaussian graphical model, a gene association network may be estimated from multiomic data based on the non-zero entries of the inverse covariance …