A three phase model to investigate the effects of dead material on the growth of avascular tumours
A three phase model to investigate the effects of dead material on the growth of avascular tumours
In vivo tumours are highly heterogeneous entities which often comprise intratumoural regions of hypoxia and widespread necrosis. In this paper, we develop a new three phase model of nutrient-limited, avascular tumour growth to investigate how dead material within the tumour may influence the tumour’s growth dynamics. We model the tumour …