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A Bayesian framework for the detection of diffusive heterogeneity

A Bayesian framework for the detection of diffusive heterogeneity

Abstract Cells are crowded and spatially heterogeneous, complicating the transport of organelles, proteins and other substrates. One aspect of this complex physical environment, the mobility of passively transported substrates, can be quantitatively characterized by the diffusion coefficient: a descriptor of how rapidly substrates will diffuse in the cell, dependent on …