Exploring the Genetic Patterns of Complex Diseases via the Integrative Genome-Wide Approach
Exploring the Genetic Patterns of Complex Diseases via the Integrative Genome-Wide Approach
Genome-wide association studies (GWASs), which assay more than a million single nucleotide polymorphisms (SNPs) in thousands of individuals, have been widely used to identify genetic risk variants for complex diseases. However, most of the variants that have been identified contribute relatively small increments of risk and only explain a small …