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Multiscale modeling of glioblastoma

Multiscale modeling of glioblastoma

As reviewed in the Editorial "Targeting glioblastoma stem-cells: a recurrent challenge in neuro-oncology" (1), we recently developed a 3D mathematical model of glioblastoma multiforme (GBM) progression and response to therapy (2).The development of the model necessarily required assumptions to be made about which key biological processes to incorporate and which …