Masking in Pragmatic Trials: Who, What, and When to Blind
Masking in Pragmatic Trials: Who, What, and When to Blind
Masking (or blinding) of treatment assignment is routinely implemented in classical randomized clinical trials (RCTs) to isolate the effect of the intervention itself and to minimize the potential for bias that could occur with traditional trials. Such biases could be introduced with the conduct, assessment of endpoints, management of conditions, …