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Advantage of Leakage of Essential Metabolites for Cells

Advantage of Leakage of Essential Metabolites for Cells

Microbial cells generally leak various metabolites including those necessary to grow. Why cells secrete even essential chemicals so often is, however, still unclear. Based on analytical and numerical calculations, we show that if the intracellular metabolism includes multibody (e.g., catalytic) reactions, leakage of essential metabolites can promote the leaking cell's …