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Nonlinear Nanomechanical Mass Spectrometry at the Single-Nanoparticle Level

Nonlinear Nanomechanical Mass Spectrometry at the Single-Nanoparticle Level

Nanoelectromechanical systems (NEMS) have emerged as a promising technology for performing the mass spectrometry of large biomolecules and nanoparticles. As nanoscale objects land on NEMS sensors one by one, they induce resolvable shifts in the resonance frequency of the sensor proportional to their weight. The operational regime of NEMS sensors …