Machine Learning to Predict Osteoporotic Fracture Risk from Genotypes
Machine Learning to Predict Osteoporotic Fracture Risk from Genotypes
Background Genomics-based prediction could be useful since genome-wide genotyping costs less than many clinical tests. We tested whether machine learning methods could provide a clinically-relevant genomic prediction of quantitative ultrasound speed of sound (SOS)—a risk factor for osteoporotic fracture. Methods We used 341,449 individuals from UK Biobank with SOS measures …