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Towards a full quantitative description of single-molecule reaction kinetics in biological cells

Towards a full quantitative description of single-molecule reaction kinetics in biological cells

The first-passage time (FPT), i.e., the moment when a stochastic process reaches a given threshold value for the first time, is a fundamental mathematical concept with immediate applications. In particular, it quantifies the statistics of instances when biomolecules in a biological cell reach their specific binding sites and trigger cellular …