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Coevolution of the mitotic and meiotic modes of eukaryotic cellular division

Coevolution of the mitotic and meiotic modes of eukaryotic cellular division

The genetic material of a eukaryotic cell comprises both nuclear DNA (ncDNA) and mitochondrial DNA (mtDNA). These differ markedly in several aspects but nevertheless must encode proteins that are compatible with one another. Here we introduce a network model of the hypothetical co-evolution of the two most common modes of …