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Covariate-constrained Randomization Routine for Achieving Baseline Balance in Cluster-randomized Trials

Covariate-constrained Randomization Routine for Achieving Baseline Balance in Cluster-randomized Trials

In cluster-randomized trials, groups or clusters of individuals, rather than individuals themselves, are randomly allocated to intervention or control. In this article, we describe a new command, ccrand, that implements a covariate-constrained randomization procedure for cluster-randomized trials. It can ensure balance of one or more baseline covariates between trial arms …