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Estimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model

Estimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model

The dynamics of tumor burden, secreted proteins or other biomarkers over time, is often used to evaluate the effectiveness of therapy and to predict outcomes for patients. Many methods have been proposed to investigate longitudinal trends to better characterize patients and to understand disease progression. However, most approaches assume a …