Predicting multicellular function through multi-layer tissue networks
Predicting multicellular function through multi-layer tissue networks
Understanding functions of proteins in specific human tissues is essential for insights into disease diagnostics and therapeutics, yet prediction of tissue-specific cellular function remains a critical challenge for biomedicine.Here, we present OhmNet , a hierarchy-aware unsupervised node feature learning approach for multi-layer networks. We build a multi-layer network, where each …