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Dynamics of Drug Resistance: Optimal Control of an Infectious Disease

Dynamics of Drug Resistance: Optimal Control of an Infectious Disease

Antimicrobial use contributes to the growing public health challenge of infectious diseases that are resistant to all but a few remaining treatments via natural selection. When few treatment options remain, should the last effective treatment be reserved for controlling larger outbreaks in the future? In “Dynamics of Drug Resistance: Optimal …