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Causal analyses, statistical efficiency and phenotypic precision through Recall-by-Genotype study design

Causal analyses, statistical efficiency and phenotypic precision through Recall-by-Genotype study design

Abstract Genome-wide association studies have been useful in identifying common genetic variants related to a variety of complex traits and diseases; however, they are often limited in their ability to inform about underlying biology. Whilst bioinformatics analyses, studies of cells, animal models and applied genetic epidemiology have provided some understanding …