Subversion of allocation concealment in a randomised controlled trial: a historical case study
Subversion of allocation concealment in a randomised controlled trial: a historical case study
If the randomisation process within a trial is subverted, this can lead to selection bias that may invalidate the trial's result. To avoid this problem, it is recommended that some form of concealment should be put into place. Despite ongoing anecdotal concerns about their susceptibility to subversion, a surprising number …