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A <i>SAS</i> Macro for Covariate-Constrained Randomization of General Cluster-Randomized and Unstratified Designs

A <i>SAS</i> Macro for Covariate-Constrained Randomization of General Cluster-Randomized and Unstratified Designs

Ivers et al. (2012) have recently stressed the importance to both statistical power and face validity of balancing allocations to study arms on relevant covariates. While several techniques exist (e.g., minimization, pair-matching, stratification), the covariateconstrained randomization (CCR) approach proposed by Moulton (2004) is favored when clusters can be recruited prior …