How to compare instrumental variable and conventional regression analyses using negative controls and bias plots
How to compare instrumental variable and conventional regression analyses using negative controls and bias plots
There is increasing interest in the use of instrumental variable analysis to overcome unmeasured confounding in observational pharmacoepidemiological studies. This is partly because instrumental variable analyses are potentially less biased than conventional regression analyses. However, instrumental variable analyses are less precise, and regulators and clinicians find it difficult to interpret …