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Understanding cancer complexome using networks, spectral graph theory and multilayer framework

Understanding cancer complexome using networks, spectral graph theory and multilayer framework

Abstract Cancer complexome comprises a heterogeneous and multifactorial milieu that varies in cytology, physiology, signaling mechanisms and response to therapy. The combined framework of network theory and spectral graph theory along with the multilayer analysis provides a comprehensive approach to analyze the proteomic data of seven different cancers, namely, breast, …