Nonparametric covariate-adjusted response-adaptive design based on a functional urn model
Nonparametric covariate-adjusted response-adaptive design based on a functional urn model
In this paper, we propose a general class of covariate-adjusted response-adaptive (CARA) designs based on a new functional urn model. We prove strong consistency concerning the functional urn proportion and the proportion of subjects assigned to the treatment groups, in the whole study and for each covariate profile, allowing the …