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Symbiotic Cell Differentiation and Cooperative Growth in Multicellular Aggregates

Symbiotic Cell Differentiation and Cooperative Growth in Multicellular Aggregates

As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as evident in quorum sensing, to achieve mutualism and division of labor. Here, to achieve stable division …