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Self controlled case series methods: an alternative to standard epidemiological study designs

Self controlled case series methods: an alternative to standard epidemiological study designs

The self controlled case series (SCCS) method is an epidemiological study design for which individuals act as their own control—ie, comparisons are made within individuals. Hence, only individuals who have experienced an event are included and all time invariant confounding is eliminated. The temporal association between a transient exposure and …