The DIAN‐TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model
The DIAN‐TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model
Abstract Introduction The Dominantly Inherited Alzheimer Network Trials Unit (DIAN‐TU) trial is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer's disease in autosomal dominant Alzheimer's disease (ADAD) families. With completion of enrollment of the first two drug arms, the DIAN‐TU now plans to …