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Competitive exclusion in a multi-strain immuno-epidemiological influenza model with environmental transmission

Competitive exclusion in a multi-strain immuno-epidemiological influenza model with environmental transmission

In this paper, a multi-strain model that links immunological and epidemiological dynamics across scales is formulated. On the within-host scale, the n strains eliminate each other with the strain having the largest immunological reproduction number persisting. However, on the population scale, we extend the competitive exclusion principle to a multi-strain …