Robust analysis of secondary phenotypes in case‐control genetic association studies
Robust analysis of secondary phenotypes in case‐control genetic association studies
The case-control study is a common design for assessing the association between genetic exposures and a disease phenotype. Though association with a given (case-control) phenotype is always of primary interest, there is often considerable interest in assessing relationships between genetic exposures and other (secondary) phenotypes. However, the case-control sample represents …