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Association of Biomarker-Based Treatment Strategies With Response Rates and Progression-Free Survival in Refractory Malignant Neoplasms
<h3>Importance</h3> The impact of a biomarker-based (personalized) cancer treatment strategy in the setting of phase 1 clinical trials was analyzed. <h3>Objective</h3> To compare patient outcomes in phase 1 studies that used a biomarker selection strategy with those that did not. <h3>Data Sources</h3> PubMed search of phase 1 cancer drug trials …