Randomized controlled trials: The technique and challenges
Randomized controlled trials: The technique and challenges
Randomised Controlled Trial (RCT) is recognised as the gold standard for testing treatment efficacy. In this article, I will explain some of the important terminologies, like randomization, stratification, allocation concealment, blinding, intention-to-treat, data monitoring committee and stopping rule, and the design of RCTs. I will also discuss the issues to …