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Reciprocity Between Robustness of Period and Plasticity of Phase in Biological Clocks

Reciprocity Between Robustness of Period and Plasticity of Phase in Biological Clocks

Circadian clocks exhibit the robustness of period and plasticity of phase against environmental changes such as temperature and nutrient conditions. Thus far, however, it is unclear how both are simultaneously achieved. By investigating distinct models of circadian clocks, we demonstrate reciprocity between robustness and plasticity: higher robustness in the period …