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The impact of covariate misclassification using generalized linear regression under covariate–adaptive randomization

The impact of covariate misclassification using generalized linear regression under covariate–adaptive randomization

Under covariate adaptive randomization, the covariate is tied to both randomization and analysis. Misclassification of such covariate will impact the intended treatment assignment; further, it is unclear what the appropriate analysis strategy should be. We explore the impact of such misclassification on the trial’s statistical operating characteristics. Simulation scenarios were …