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Extrapolating Survival from Randomized Trials Using External Data: A Review of Methods

Extrapolating Survival from Randomized Trials Using External Data: A Review of Methods

This article describes methods used to estimate parameters governing long-term survival, or times to other events, for health economic models. Specifically, the focus is on methods that combine shorter-term individual-level survival data from randomized trials with longer-term external data, thus using the longer-term data to aid extrapolation of the short-term …