Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review
Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review
Background Personalized medicine is a growing area of research which aims to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomarker. Prior to utilizing a patient's …