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An evaluation of constrained randomization for the design and analysis of group‐randomized trials

An evaluation of constrained randomization for the design and analysis of group‐randomized trials

In group-randomized trials, a frequent practical limitation to adopting rigorous research designs is that only a small number of groups may be available, and therefore, simple randomization cannot be relied upon to balance key group-level prognostic factors across the comparison arms. Constrained randomization is an allocation technique proposed for ensuring …