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The use of multiple imputation (MI) in cluster randomised trials with suspected missing not at random (MNAR) outcome

The use of multiple imputation (MI) in cluster randomised trials with suspected missing not at random (MNAR) outcome

Introduction: The HELP trial of a healthy lifestyle and eating programme for obese pregnant women resulted in a final response rate of 70%. More women in the intervention arm than the control arm were lost to follow-up, leading the trial team to suspect a MNAR mechanism for missing outcome data. …