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Multiple imputation for IPD meta‐analysis: allowing for heterogeneity and studies with missing covariates

Multiple imputation for IPD meta‐analysis: allowing for heterogeneity and studies with missing covariates

Recently, multiple imputation has been proposed as a tool for individual patient data meta‐analysis with sporadically missing observations, and it has been suggested that within‐study imputation is usually preferable. However, such within study imputation cannot handle variables that are completely missing within studies. Further, if some of the contributing studies …