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Using the False Discovery Rate Approach in the Genetic Dissection of Complex Traits: A Response to Weller et al.

Using the False Discovery Rate Approach in the Genetic Dissection of Complex Traits: A Response to Weller et al.

WELLER et al. ([1998][1]) proposed controlling the ā€œfalse discovery rateā€ (FDR) or the expected proportion of false rejections within the class of rejected null hypotheses when performing preliminary genome scans, adopting the method of Benjamini and Hochberg ([1995][2]; hereafter BH). The BH