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Sources of variation in false discovery rate estimation include sample size, correlation, and inherent differences between groups

Sources of variation in false discovery rate estimation include sample size, correlation, and inherent differences between groups

High-throughtput technologies enable the testing of tens of thousands of measurements simultaneously. Identification of genes that are differentially expressed or associated with clinical outcomes invokes the multiple testing problem. False Discovery Rate (FDR) control is a statistical method used to correct for multiple comparisons for independent or weakly dependent test …