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The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey

The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey

Statistical tests for funnel-plot asymmetry are common in meta-analyses. Inappropriate application can generate misleading inferences about publication bias. We aimed to measure, in a survey of meta-analyses, how frequently the application of these tests would be not meaningful or inappropriate.We evaluated all meta-analyses of binary outcomes with é 3 studies …