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Statistical analysis and handling of missing data in cluster randomised trials: protocol for a systematic review

Statistical analysis and handling of missing data in cluster randomised trials: protocol for a systematic review

Cluster randomised trials (CRTs) randomise participants in groups, rather than as individuals, and are key tools used to assess interventions in health research where treatment contamination is likely or if individual randomisation is not feasible. Missing outcome data can reduce power in trials, including in CRTs, and is a potential …