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Random Matrix Approach to Collective Behavior and Bulk Universality in Protein Dynamics

Random Matrix Approach to Collective Behavior and Bulk Universality in Protein Dynamics

Covariance matrices of amino acid displacements, commonly used to characterize the large-scale movements of proteins, are investigated through the prism of random matrix theory. Bulk universality is detected in the local spacing statistics of noise-dressed eigenmodes, which is well described by a Brody distribution with parameter $\ensuremath{\beta}\ensuremath{\simeq}0.8$. This finding, supported …