A logistic regression based extension of the TDT for continuous and categorical traits
A logistic regression based extension of the TDT for continuous and categorical traits
The transmission disequilibrium test (TDT), designed as a test of linkage in the presence of association (i.e. linkage disequilibrium), has received considerable attention in the recent statistical genetics literature due to its advantages over other within-family analytic methods. One limitation of the conventional TDT is its application solely to linkage …