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Functional immunomics: Microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes
One's present repertoire of antibodies encodes the history of one's past immunological experience. Can the present autoantibody repertoire be consulted to predict resistance or susceptibility to the future development of an autoimmune disease? Here, we developed an antigen microarray chip and used bioinformatic analysis to study a model of type …