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Glass Transition in Biomolecules and the Liquid-Liquid Critical Point of Water

Glass Transition in Biomolecules and the Liquid-Liquid Critical Point of Water

Using molecular dynamics simulations, we investigate the relation between the dynamic transitions of biomolecules (lysozyme and DNA) and the dynamic and thermodynamic properties of hydration water. We find that the dynamic transition of the macromolecules, sometimes called a ``protein glass transition,'' occurs at the temperature of dynamic crossover in the …