Beneficial Mutation–Selection Balance and the Effect of Linkage on Positive Selection
Beneficial Mutation–Selection Balance and the Effect of Linkage on Positive Selection
Abstract When beneficial mutations are rare, they accumulate by a series of selective sweeps. But when they are common, many beneficial mutations will occur before any can fix, so there will be many different mutant lineages in the population concurrently. In an asexual population, these different mutant lineages interfere and …